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You may have heard this term used in reference to accident or paralysis victims: "his muscles atrophied because of non-use".
Exposure to certain chemicals can cause internal organs to degrade, weaken and decrease in size, particularly with chronic (long-term) exposure. While muscles can be rehabilitated through exercise, it is fairly tough to give your kidneys or liver a strength-building workout!
See also: chronic, myalgia.
Additional definitions from Google and OneLook.
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