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Atrophy
Definition
Atrophy is a wasting or decrease in size of a bodily organ, tissue, or part owing to disease, injury, or lack of use.
You may have heard this term used in reference to accident or paralysis victims: "his muscles atrophied because of non-use".
SDS Relevance
This term normally appears in Section 11 (toxicological information) of a Safety Data Sheet as a chronic health effect of exposure to the substance.
Exposure to certain chemicals can cause internal organs to degrade, weaken and decrease in size, particularly with chronic (long-term) exposure. For example, industrial solvents have been known to cause brain atrophy. While muscles can be rehabilitated through exercise, it is fairly tough to give your kidneys, liver or brain a strength-building workout!
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Further Reading
- Occupational Exposure to Solvents: Neuropsychiatric and Imaging Features from J Neuropsychiatry 2015, 27(1), 1-6.
- Organic brain damage and occupational solvent exposure from Brit J Ind Medicine 1992, 49, 776-781.
- Neurotoxicity of solvent mixtures in spray painters from Int Arch Occup Eng Health 1992, 64(5), 361-372.
- Brain Atrophy and Alzheimer's from Mayo Clinic.
- Cerebral Atrophy at Baptist Health.
- Muscle Atrophy, an article in the MedLinePlus Encylcopedia at the National Institutes of Health.
- Muscle Atrophy at the Cleveland Clinic.
- What Causes Muscle Wasting? at Healthline.
- What to know about muscle atrophy at MedicalNewsToday.
- What Is Atrophic Kidney and How Is It Treated? at Healthline.com.
See also: chronic, myalgia, neurotoxin.