| The Home page of ILPI's Safety Data Sheet (SDS) Resource, the leader in SDS information since 1995! | |
| The history and philosophy behind this resource. | |
| A curated collection of books and reference materials concerning Safety Data Sheets and closely related topics. | |
| Paste your plain text SDS into the SDS-Demystifier, and it will be converted into a hypertext-enriched document with links to detailed explanations of each key term. | |
| An extensive list of frequently asked questions about Safety Data Sheets including regulations, content, compliance, and more. | |
| A humorous take on Safety Data Sheet jargon. Fill in the blanks on our entry form to generate a personalized Unsafety Data Sheet to share with your coworkers. | |
| Since 1995, we've maintained this massive curated list of the best places to find Safety Data Sheets on the Internet. | |
| Way more than a glossary, this hypertext-enhanced resource covers hundreds of SDS-related terms and expert knowledge. Each entry includes both the SDS relevance and links to additional authoritative resources. | |
| Archived results of Safety Data Sheet related polls taken by some of our millions of site visitors | |
| You are here! The OSHA regulations behind SDS regulations, including the inspection guidelines and over 400 official interpretations letters under the Hazard Communication Standard | |
| Commercial suppliers of SDS authoring and management software as well as cloud compliance services. | |
| Commercial companies that will create SDS's for your specific needs as well as SDS translation companies. |
Interactive Learning Paradigms, Incorporated
Safety signs, banners, and scoreboards? Get yours at Safety Emporium!
| Title: 09/17/1987 - Definitions of target organ and hazards of chemicals under the Hazard Communication Standard. | |
| Record Type: Interpretation | Standard Number: 1910.1200 |
ILPI Notes: This interpretation is based on and references the original HCS 1986 which, along with HCS 1994 is now obsolete. It references portions of the standard that have since been deleted or changed. While the answer to Questions 1 is still generally correct except for the references to the obsolete standards, the answer for Questions 2 and 3 are no longer valid under the current regulation which expanded the definition of health hazard. This letter is presented for historical purposes only.
September 17, 1987
Mr. Frank L. Pellegrini
Law Offices
A Professional Corporation
Suite 400, Chouteau Center
133 South Eleventh Street
St. Louis, Missouri 63102
Dear Mr. Pellegrini:
This is in response to your letter of July 21 concerning the Hazard Communication Standard, 29 CFR 1910.1200 [in context: HCS 1994 | current regulation: HCS 2012].
Your questions and our responses are as follow:
Question 1: Define target organs.Answer:As defined in Casarett and Doull'e Toxicology, the Basic Science of Poisons, Most chemicals that produce systemic toxicity do not cause a similar degree of toxicity in all organs but usually produce the major toxicity to one or two organs. These are referred to as target organs of toxicity for that chemical.
Appendix A of the Hazard Communication Standard [in context: HCS 1994 | current regulation: HCS 2012] provides a target organ categorization of effects chemicals which have been found to cause such effects. The examples given are presented to illustrate the range and diversity of effects and hazards but are not intended to be all-inclusive.
Question 2: After defining same, please advise where a manufacturer can obtain a list of target organs versus hazardous chemicals.
Answer: As stated in our June 29 letter, Appendix C of the standard [in context: HCS 1994 | current regulation: HCS 2012 Appendix A and Appendix F] provides a list of available data sources which can be used to determine the target organ effects of chemicals.
Question 3: Define hazards of chemicals.
Safety Emporium carries warning, directional, aisle marking, glow in the dark, reflective, and fluorescent tapes plus a whole lot more.
[NOTE: This following answer is obsolete. See the comparison of HCS 1994 and 2012]
Answer: The Hazard Communication Standard defines "hazardous chemical" to mean any chemical which is a physical or a health hazard.
"Physical hazard" means a chemical for which there is scientifically valid evidence that it is a combustible liquid, a compressed gas, explosive, flammable, an organic peroxide, an oxidizer, pyrophoric, unstable (reactive) or water-reactive.
"Health hazard" means a chemical for which there is statistically significant evidence based on at least one study conducted in accordance with established scientific principles that acute or chronic health effects may occur in exposed employees. The term "health hazard" includes chemicals which are carcinogens, toxic or highly toxic agents, reproductive toxins, irritants, corrosives, sensitizers, hepatotoxins, nephrotoxins, agents which act on the hematopoietic system, and agents which damage the lungs, skin, eyes, or mucous membranes. Appendix A [in context: HCS 1994 | current regulation: HCS 2012] provides further definitions and explanations of the scope of health hazards covered and Appendix B [in context: HCS 1994 | current regulation: HCS 2012] describes the criteria to be used to determine whether or not a chemical is to be considered hazardous for purposes of the standard.
If I can be of further assistance, please feel free to contact me again.
Sincerely,
Thomas J. Shepich, Director
Directorate of Compliance Assistance
The original official public domain version of this document is available from OSHA at XXXOSHAURL.