From: Boitumelo Kgarebe <bkgarebe**At_Symbol_Here**GMAIL.COM>
Subject: Re: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)
Date: Mon, 17 Sep 2018 18:57:48 +0200
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: CAOAbd9184v3+xzaSrQGrqMmZPC2eJZrgmncy7QoKqevHXWtGwQ**At_Symbol_Here**mail.gmail.com
In-Reply-To <165e80a4de8-1ec5-960a**At_Symbol_Here**webjas-vac186.srv.aolmail.net>


Many thanks Monona. So wherether it is resin-bonded does not negate the effects? Any substitute products?
Regards
BVK

On Mon, 17 Sep 2018, 17:03 Monona Rossol, <0000030664c37427-dmarc-request**At_Symbol_Here**lists.princeton.edu> wrote:
Pulled right off Sigma Aldrich's SDS for triglycidyl isocyanurate (TGIC)

Respiratory or skin sensitisation
Maximisation Test - Guinea pig
Result: May cause sensitisation by skin contact.
(OECD Test Guideline 406)

Note European spellings. The reason you can usually trust Sigma's SDSs is they are E.U. compliant since they export. The U.S. SDS are still rotten.

Monona Rossol, M.S., M.F.A., Industrial Hygienist
President: Arts, Crafts & Theater Safety, Inc.
Safety Officer: Local USA829, IATSE
181 Thompson St., #23
New York, NY 10012 212-777-0062
actsnyc**At_Symbol_Here**cs.com www.artscraftstheatersafety.org



-----Original Message-----
From: Boitumelo Kgarebe <bkgarebe**At_Symbol_Here**GMAIL.COM>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Sent: Mon, Sep 17, 2018 8:47 am
Subject: Re: [DCHAS-L] Question on triglycidyl isocyanurate (TGIC)

Dear Colleagues,
Our Occupational Medicine clinic saw two patients who were from the same company, performing the same duties, namely powder spray coating using a chemical called triglycidyl isocyanurate (TGIC). They were assessed and the clinic seemed convinced that this chemical is a sensitizer, causing their occupational condition.
A factory visit to understand exposures and associated occupational setting well, was also undertaken . The process observed was similar to what is described in literature.
The Factory Management seems to be keen that we investigate this further, as they are adamant this chemical is not the likely cause of their respiratory (asthmatic) effects. Another point from the company is that the TGIC is actually bound to a resin thus not active on its own as it is already in a bound state (not freely available).
My question is: Is TGIC found in the sample/ that they use is freely available as a sensitiser? Are there other less harmful substitutes?
BVK
Dr Boitumelo V. Kgarebe Phd(London) FAAS
Head: Analytical Services
25 Hospital Street, JHB 2001
National Institute for Occupational Health
National Health Laboratory Service
Tel: +27(0)11 712 6410 | Mobile: +27(0)82 | Fax: +27(0) 712 6545
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