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Date: Thu, 9 Nov 2006 17:41:17 -0500
Reply-To: List Moderator <esf**At_Symbol_Here**UVM.EDU>
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From: List Moderator <esf**At_Symbol_Here**UVM.EDU>
Subject: HPLC pressure certification

	From: 	  regina.cody**At_Symbol_Here**nasa.gov
	Date: 	November 9, 2006 5:34:07 PM EST (CA)

One of my colleagues has two HPLC (High Precision Liquid  
Chromatography) instruments in his lab; one is a standard instrument  
and one is a so called nanoflow UPLC (Ultra Precision Liquid  
Chromatography) specialized for very sensitive analysis with flow  
rates of 100 nanoliters (nL) per minute and operating pressures up to  
10,000 psi.  Sometime ago a Headquarters safety team conducted an  
inspection and cited these instruments as requiring pressure  
certification by our center people who do pressure certifications.   
It appears that neither the Headquarters safety people nor our center  
certification manager is familiar with liquid chromatography  
instruments.  We need to respond to this finding soon.  Does anyone  
have or know of a risk analysis for pressure on this type of  
instrumentation?  If anyone else has been in this situation, what was  
your response to the safety finding and how was the situation resolved?
Thank you for any help you can give us.

Regina Cody

Regina J. Cody
NASA Goddard Space Flight Center
Code 691
Greenbelt, MD 20771
Phone: 301-286-3782
FAX: 301-286-1683
E-mail: regina.cody**At_Symbol_Here**nasa.gov

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