From: Edward J. Sare <sage7652**At_Symbol_Here**BELLSOUTH.NET>
Subject: Re: [DCHAS-L] Papers on risks of scaling up reactions
Date: Tue, 25 Sep 2018 12:21:41 -0400
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: F106C180-2621-4CBD-AB71-F89912DEED55**At_Symbol_Here**bellsouth.net
In-Reply-To <5dbf8006-e63c-03cf-4cf7-3af730d89856**At_Symbol_Here**appstate.edu>


Suggest you contact Netzsch.  Would imagine they have lots of information available in support of sales of their accelerating rate calorimeter (ARC), which is so very useful for the safe scale up of exothermic reactions.

Ed Sare

On Sep 25, 2018, at 11:38 AM, Samuella Beth Sigmann <sigmannsb**At_Symbol_Here**APPSTATE.EDU> wrote:

You could use the Texas Tech incident that the CSB investigated.

https://www.csb.gov/texas-tech-university-chemistry-lab-explosion/
Sammye


On 9/25/2018 11:04 AM, Jeffrey R. Cogswell wrote:

Hello

I'm currently working on a safety talk about RAMP and decided to include a section on "RAMPing up Reactions"

It was discussed at ACS that scaling up reactions is a under-stated danger in many chemistry laboratories.

 

Does anyone have any suggestion for articles that talks about or quantifies the risks of increasing the yield in chemical reactions?

 

For example: https://ac.els-cdn.com/S1871553213006178/1-s2.0-S1871553213006178-main.pdf?_tid=672cf49d-0170-4ff1-8b06-85bc88bda807&acdnat=1537887055_4baf3ea46cec9ef7b4cb51c2aba76bf8 I found very informative and it would be great to find more sources.

 

Thanks

 

Jeffrey R. Cogswell, Ph.D.

Chemical Inventory and Laboratory Resource Center Technician, EHS

37 Dewey Field Road, HB 6216

Hanover, New Hampshire 03755

http://www.dartmouth.edu/~ehs/

 

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We, the willing, led by the unknowing, are doing the impossible for the ungrateful. We have done so much, for so long, with so little, we are now qualified to do everything with nothing. Teresa Arnold paraphrased from Konstantin Josef Jire=C4=8Dek (1854 =E2=80" 1918)

 

Samuella B. Sigmann, MS, NRCC-CHO

Senior Lecturer/Safety Committee Chair/Director of Stockroom

A. R. Smith Department of Chemistry

Appalachian State University

525 Rivers Street

Boone, NC 28608

Phone: 828 262 2755

Fax: 828 262 6558

Email: sigmannsb**At_Symbol_Here**appstate.edu

 

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