From: "McCallion, George (G)" <GMcCallion**At_Symbol_Here**DOW.COM>
Subject: Re: [DCHAS-L] Question: working with high potent compounds
Date: Tue, 11 Feb 2014 12:53:54 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: 54EE680479B80F4AA0B0D04355A3D71D5682E5**At_Symbol_Here**046-CH1MPN1-101.046d.mgd.msft.net
In-Reply-To


Nadejda,

 

In my previous employment within Pharma under Preclinical Development, I worked with Cytotoxins on a daily basis. Aside from the PAPR, dedicated fume hoods & equipment We had a I/D rating system (I=inhalation, D=Dermal). But we also assigned the ratings based on LD50 values that were provided to us.

 

But I agree with Margaret in the need for additional clarification. Keep in mind that high hazard and toxic are not the same, although many people use them as if they were equivalent.

 

I’ll try to lend any assistance in regards to your query.

 

Sincerely,

George

 

***********************************************

George D. McCallion, Chemist

The Dow Chemical Company

Functional Coatings R&D

Mail Stop S23
400 Arcola Road

P.O. Box 7000

Collegeville, PA 19426

Phone: 610.244.6504

E-mail: GMcCallion**At_Symbol_Here**dow.com

***********************************************

 

 

From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**MED.CORNELL.EDU] On Behalf Of Margaret Rakas
Sent: Monday, February 10, 2014 10:16 AM
To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Subject: Re: [DCHAS-L] Question: working with high potent compounds

 

Hi Nadia,

 

I don't know if others have responded privately to you but if you haven't had any responses it might be because (at least to me) I am unsure of what you mean by 'high potent" chemicals.  Do you mean highly (or acutely) toxic?  Do you mean 'potent' in terms of pharmaceutical properties?  Or something else entirely?

Please disregard my inquiry if you have already received some assistance off-line.

Margaret

 

On Sat, Feb 8, 2014 at 9:07 PM, Nadejda Spassova <nspassova**At_Symbol_Here**delmarchem.com> wrote:

Hi all,
I am just trying to find some information regarding high potent compounds, how they classify, what that mean in term of toxicology, exposure limits, rules to follow when working with this kind of molecules.
Does anyone have a policy for working with high potent chemicals.
Thanks in advance,
Nadia

-----Message d'origine-----
De : DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**MED.CORNELL.EDU] De la part de Secretary, ACS Division of Chemical Health and Safety
Envoy=E9 : 21 ao=FBt 2013 07:53
=C0 : DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Objet : [DCHAS-L] Chemical Safety Tweets

Chemical Safety Headlines From Google
Wednesday, August 21, 2013 7:49:32 AM

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labsustain "Automated Alternative Chemical, Product, & Process Risk Assessment Workshop Sep 24, 2013,.North Bethesda, MD, USA" http://t.co/wqlZ97JB3q

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labsustain CDC - - Nanotechnology - 10 Critical Topic Areas - NIOSH Workplace Safety and Health Topic http://t.co/efPHWAo2BW [http://t.co/RTDukkqTVF]

acsdchas Controlling Formaldehyde Exposures in an Academic Gross Anatomy Laboratory http://t.co/Tgi1AFswJ9

acsdchas Catalysis in Green Chemistry Symposium October 4, 2013 Rutgers Busch Campus Piscataway, New Jersey, USA " http://t.co/KSFmSIq6XM

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acsdchas RT **At_Symbol_Here**NIOSH: What to do if exposed to blood or other body fluids http://t.co/yIT4bKfUFG #healthcare #ems

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acsdchas CDC - - Nanotechnology - 10 Critical Topic Areas - NIOSH Workplace Safety and Health Topic http://t.co/k3JYamVAiB [http://t.co/CBhlX4Ubwe]

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Ralph Stuart
secretary**At_Symbol_Here**dchas.org
Secretary
Division of Chemical Health and Safety
American Chemical Society



 

--
Margaret A. Rakas, Ph.D.
Manager, Inventory & Regulatory Affairs
Clark Science Center
413-585-3877 (p)

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